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|Title:||Characteristics and appearance of the normal optic nerve head in 6-year-old children|
|Source:||Samarawickrama, C., Pai, A., Tariq, Y., Healey, P.R., Wong, T.Y., Mitchell, P. (2012-01). Characteristics and appearance of the normal optic nerve head in 6-year-old children. British Journal of Ophthalmology 96 (1) : 68-72. ScholarBank@NUS Repository. https://doi.org/10.1136/bjo.2010.197426|
|Abstract:||Aim: To document planimetric measures of normal optic nerve head parameters in 6-year-old children and to report prevalence and associations of common optic nerve signs. Methods: The Sydney Childhood Eye Study examined 1765 children aged 6 years. Complete retinal photographs were available for 1225 participants, captured using a digital camera. Optical coherence tomography optic-disc measurements were acquired using the 'fast' optic-disc protocol. Statistical analyses were conducted using SAS version 9.1.3. Results: The mean (95% CIs) planimetric optic-disc area was 2.29 mm 2 (2.27 to 2.32), mean cup area 0.48 mm 2(0.47 to 0.50), mean vertical disc diameter 1.81 mm (1.80 to 1.82) and mean vertical cup diameter 0.72 mm (0.71 to 0.73), resulting in a mean vertical cup/disc ratio of 0.40 (0.39 to 0.40). Similarities existed between vertical, horizontal and area cup/disc ratios (p>0.05) measured by planimetry and optical coherence tomography, but only for vertical disc diameters between 1.75 and 1.96 mm. Visible lamina cribrosa pores were present in 4.9%. This sign was associated with larger optic nerve parameters. The prevalence of optic disc tilt and cyclotorsion was 1.6% and 8.7%, respectively, and the prevalence of α- and β-peripapillary atrophy was 43.3% and 20.2%, respectively. Neither sign was associated with myopia, after adjusting for age, sex and ethnicity, although eyes with β-peripapillary atrophy had a longer mean axial length (p=0.04). Cilioretinal arteries were present in 27% and tended to be located temporally. Conclusions The mean vertical cup/disc ratio was 0.4 in this 6-year-old sample. Planimetric optic nerve head measures and population prevalence findings for optic disc signs in this population could be regarded as normative data for ophthalmologists in clinical settings.|
|Source Title:||British Journal of Ophthalmology|
|Appears in Collections:||Staff Publications|
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