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|Title:||Associations of retinal microvascular signs and intracranial large artery disease|
|Authors:||De Silva, D.A.|
|Keywords:||intracranial large artery disease|
|Citation:||De Silva, D.A., Manzano, J.J.F., Woon, F.-P., Liu, E.Y., Lee, M.-P., Gan, H.-Y., Chen, C.P.L.H., Chang, H.-M., Mitchell, P., Wang, J.J., Lindley, R.I., Wong, T.-Y., Wong, M.-C. (2011-03). Associations of retinal microvascular signs and intracranial large artery disease. Stroke 42 (3) : 812-814. ScholarBank@NUS Repository. https://doi.org/10.1161/STROKEAHA.110.589960|
|Abstract:||BACKGROUND AND PURPOSE - Intracranial large artery disease (ICLAD) is a major cause of ischemic stroke. Retinal microvascular changes are associated with stroke, including small vessel cerebral disease and extracranial carotid disease. We examined the relationship between ICLAD and retinal microvascular changes. METHODS - This is a prospective cohort of 802 acute ischemic stroke patients. Retinal changes were assessed from photographs by graders masked to clinical data. ICLAD was evaluated using prespecified criteria. RESULTS - ICLAD was not associated with ipsilateral retinal arteriolar/venular caliber, focal arteriolar narrowing, or arteriovenous nicking. Severe enhanced arteriolar light reflex was independently associated with any ICLAD (P=0.006) and severe ICLAD (P|
|Appears in Collections:||Staff Publications|
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