Please use this identifier to cite or link to this item: https://doi.org/10.1161/STROKEAHA.110.589960
Title: Associations of retinal microvascular signs and intracranial large artery disease
Authors: De Silva, D.A.
Manzano, J.J.F.
Woon, F.-P.
Liu, E.Y.
Lee, M.-P.
Gan, H.-Y.
Chen, C.P.L.H.
Chang, H.-M.
Mitchell, P.
Wang, J.J.
Lindley, R.I.
Wong, T.-Y. 
Wong, M.-C.
Keywords: intracranial large artery disease
retina
stroke
Issue Date: Mar-2011
Citation: De Silva, D.A., Manzano, J.J.F., Woon, F.-P., Liu, E.Y., Lee, M.-P., Gan, H.-Y., Chen, C.P.L.H., Chang, H.-M., Mitchell, P., Wang, J.J., Lindley, R.I., Wong, T.-Y., Wong, M.-C. (2011-03). Associations of retinal microvascular signs and intracranial large artery disease. Stroke 42 (3) : 812-814. ScholarBank@NUS Repository. https://doi.org/10.1161/STROKEAHA.110.589960
Abstract: BACKGROUND AND PURPOSE - Intracranial large artery disease (ICLAD) is a major cause of ischemic stroke. Retinal microvascular changes are associated with stroke, including small vessel cerebral disease and extracranial carotid disease. We examined the relationship between ICLAD and retinal microvascular changes. METHODS - This is a prospective cohort of 802 acute ischemic stroke patients. Retinal changes were assessed from photographs by graders masked to clinical data. ICLAD was evaluated using prespecified criteria. RESULTS - ICLAD was not associated with ipsilateral retinal arteriolar/venular caliber, focal arteriolar narrowing, or arteriovenous nicking. Severe enhanced arteriolar light reflex was independently associated with any ICLAD (P=0.006) and severe ICLAD (P
Source Title: Stroke
URI: http://scholarbank.nus.edu.sg/handle/10635/109206
ISSN: 00392499
DOI: 10.1161/STROKEAHA.110.589960
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