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https://doi.org/10.1371/journal.pgen.1001127
| Title: | Identification of new genetic risk variants for Type 2 Diabetes | Authors: | Shu, X.O. Long, J. Cai, Q. Qi, L. Xiang, Y.-B. Cho, Y.S. Tai, E.S. Li, X. Lin, X. Chow, W.-H. Go, M.J. Seielstad, M. Bao, W. Li, H. Cornelis, M.C. Yu, K. Wen, W. Shi, J. Han, B.-G. Sim, X.L. Liu, L. Qi, Q. Kim, H.-L. Ng, D.P.K. Lee, J.-Y. Kim, Y.J. Li, C. Gao, Y.-T. Zheng, W. Hu, F.B. |
Issue Date: | Sep-2010 | Citation: | Shu, X.O., Long, J., Cai, Q., Qi, L., Xiang, Y.-B., Cho, Y.S., Tai, E.S., Li, X., Lin, X., Chow, W.-H., Go, M.J., Seielstad, M., Bao, W., Li, H., Cornelis, M.C., Yu, K., Wen, W., Shi, J., Han, B.-G., Sim, X.L., Liu, L., Qi, Q., Kim, H.-L., Ng, D.P.K., Lee, J.-Y., Kim, Y.J., Li, C., Gao, Y.-T., Zheng, W., Hu, F.B. (2010-09). Identification of new genetic risk variants for Type 2 Diabetes. PLoS Genetics 6 (9) : -. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pgen.1001127 | Abstract: | Although more than 20 genetic susceptibility loci have been reported for type 2 diabetes (T2D), most reported variants have small to moderate effects and account for only a small proportion of the heritability of T2D, suggesting that the majority of inter-person genetic variation in this disease remains to be determined. We conducted a multistage, genome-wide association study (GWAS) within the Asian Consortium of Diabetes to search for T2D susceptibility markers. From 590,887 SNPs genotyped in 1,019 T2D cases and 1,710 controls selected from Chinese women in Shanghai, we selected the top 2,100 SNPs that were not in linkage disequilibrium (r2 | Source Title: | PLoS Genetics | URI: | http://scholarbank.nus.edu.sg/handle/10635/108414 | ISSN: | 15537390 | DOI: | 10.1371/journal.pgen.1001127 |
| Appears in Collections: | Staff Publications Elements |
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