Please use this identifier to cite or link to this item: https://doi.org/10.1111/j.1549-8719.2010.00033.x
Title: Association between physical activity and retinal microvascular signs: The atherosclerosis risk in communities (ARIC) study
Authors: Tikellis, G.
Anuradha, S.
Klein, R.
Wong, T.Y. 
Keywords: arteriovenous nicking
physical activity
retinal vascular caliber
retinopathy
Issue Date: Jul-2010
Citation: Tikellis, G., Anuradha, S., Klein, R., Wong, T.Y. (2010-07). Association between physical activity and retinal microvascular signs: The atherosclerosis risk in communities (ARIC) study. Microcirculation 17 (5) : 381-393. ScholarBank@NUS Repository. https://doi.org/10.1111/j.1549-8719.2010.00033.x
Abstract: Objective: To examine the association between physical activity measured during leisure, sport, and work and retinal microvascular signs. Methods: Participants of the Atherosclerosis Risk in Communities (ARIC) Study, a population-based cross-sectional study, had retinal photographs taken at their third follow up visit (1993-1995). Retinal microvascular signs were assessed using a standardized protocol and retinal vascular caliber by a computer-assisted method. Leisure, sport, and work-related physical activity levels were determined through a modified Baecke physical activity questionnaire. Results: A higher level of physical activity during sport and work was significantly associated with a lower prevalence of arteriovenous (AV) nicking, wider venular caliber, and retinopathy. In multivariate models, persons with a level of sport-related physical activity above the median were less likely to have AV nicking (odds ratio [OR] = 0.87; 95% confidence interval [CI] 0.78-0.97) and wider retinal venules (OR = 0.91; 95% CI: 0.83-0.99). Persons with a level of work-related physical activity above the median were less likely to have diabetic retinopathy (OR = 0.66, 95% CI: 0.51-0.85). Conclusions: In this cross-sectional analyzes, higher levels of physical activity was associated with a lower prevalence of retinal microvascular abnormalities. © 2010 John Wiley & Sons Ltd.
Source Title: Microcirculation
URI: http://scholarbank.nus.edu.sg/handle/10635/108266
ISSN: 10739688
DOI: 10.1111/j.1549-8719.2010.00033.x
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