Please use this identifier to cite or link to this item:
|Title:||Proteomic identification of Ku70/Ku80 autoantigen recognized by monoclonal antibody against hepatocellular carcinoma|
|Source:||Luk, J.M., Su, Y.C.F., Lam, S.C.T., Lee, C.K., Hu, M.Y., He, Q.Y., Lau, G.K., Wong, F.W.S., Fan, S.-T. (2005-05). Proteomic identification of Ku70/Ku80 autoantigen recognized by monoclonal antibody against hepatocellular carcinoma. Proteomics 5 (7) : 1980-1986. ScholarBank@NUS Repository. https://doi.org/10.1002/pmic.200401084|
|Abstract:||A murine monoclonal antibody (mAb), CLD3 (IgG1,κ), was generated against hepatocellular carcinoma (HCC). Both immunofluorescence and immunohistochemical assays indicated the reactivity of CLD3 mAb localized at the nucleus and/or cytoplasm of tumorigenic HCC cell lines as well as in liver cancer tissues. By immunoprecipitation and using the matrix-assisted laser desorption/ionization-time of flight mass spectrometry approach, the antigenic specificity of CLD3 was determined to be heterodimeric Ku70 and Ku80 autoantigen, which was confirmed by Western blotting. © 2005 WILEY-VCH Verlag GmbH & Co. KGaA.|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Dec 13, 2017
WEB OF SCIENCETM
checked on Nov 16, 2017
checked on Dec 10, 2017
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.