Please use this identifier to cite or link to this item: https://doi.org/10.1111/j.1365-2141.2008.07261.x
Title: An international standardization programme towards the application of gene expression profiling in routine leukaemia diagnostics: The Microarray Innovations in LEukemia study prephase
Authors: Kohlmann, A.
Kipps, T.J.
Rassenti, L.Z.
Downing, J.R.
Shurtleff, S.A.
Mills, K.I.
Gilkes, A.F.
Hofmann, W.-K.
Basso, G.
Dell'Orto, M.C.
Foà, R.
Chiaretti, S.
De Vos, J.
Rauhut, S.
Papenhausen, P.R.
Hernández, J.M.
Lumbreras, E.
Yeoh, A.E. 
Koay, E.S. 
Li, R.
Liu, W.-M.
Williams, P.M.
Wieczorek, L.
Haferlach, T.
Keywords: Diagnostics
Gene expression profiling
Leukaemia
Microarray
Standardization
Issue Date: Sep-2008
Source: Kohlmann, A., Kipps, T.J., Rassenti, L.Z., Downing, J.R., Shurtleff, S.A., Mills, K.I., Gilkes, A.F., Hofmann, W.-K., Basso, G., Dell'Orto, M.C., Foà, R., Chiaretti, S., De Vos, J., Rauhut, S., Papenhausen, P.R., Hernández, J.M., Lumbreras, E., Yeoh, A.E., Koay, E.S., Li, R., Liu, W.-M., Williams, P.M., Wieczorek, L., Haferlach, T. (2008-09). An international standardization programme towards the application of gene expression profiling in routine leukaemia diagnostics: The Microarray Innovations in LEukemia study prephase. British Journal of Haematology 142 (5) : 802-807. ScholarBank@NUS Repository. https://doi.org/10.1111/j.1365-2141.2008.07261.x
Abstract: Gene expression profiling has the potential to enhance current methods for the diagnosis of haematological malignancies. Here, we present data on 204 analyses from an international standardization programme that was conducted in 11 laboratories as a prephase to the Microarray Innovations in LEukemia (MILE) study. Each laboratory prepared two cell line samples, together with three replicate leukaemia patient lysates in two distinct stages: (i) a 5-d course of protocol training, and (ii) independent proficiency testing. Unsupervised, supervised, and r 2 correlation analyses demonstrated that microarray analysis can be performed with remarkably high intra-laboratory reproducibility and with comparable quality and reliability. © 2008 The Authors.
Source Title: British Journal of Haematology
URI: http://scholarbank.nus.edu.sg/handle/10635/107510
ISSN: 00071048
DOI: 10.1111/j.1365-2141.2008.07261.x
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

76
checked on Feb 26, 2018

WEB OF SCIENCETM
Citations

66
checked on Feb 26, 2018

Page view(s)

38
checked on Apr 20, 2018

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.