Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/107407
Title: BIOFABRICATION AND CHARACTERIZATION OF MENISCAL SCAFFOLDS VIA AN ELECTROHYDRODYNAMIC JET PRINTING TECHNIQUE
Authors: LI JINLAN
Keywords: Electrohydrodynamic jet printing, Fibers, Three-dimensional, Tissue engineering, Scaffolds, Meniscus,
Issue Date: 26-Jun-2014
Citation: LI JINLAN (2014-06-26). BIOFABRICATION AND CHARACTERIZATION OF MENISCAL SCAFFOLDS VIA AN ELECTROHYDRODYNAMIC JET PRINTING TECHNIQUE. ScholarBank@NUS Repository.
Abstract: CLINICAL NEEDS IN MENISCAL INJURIES HAVE LED TO THE SEARCH FOR A TISSUE-ENGINEERED BIOMETRIC SCAFFOLD THAT CAN REPLACE DAMAGED MENISCUS, BOTH ANATOMICALLY AND FUNCTIONALLY. EXISTING SCAFFOLDING TECHNOLOGIES HAVE YET TO YIELD SUSTAINED, RELIABLE LONG-TERM RESULTS DUE TO THE INABILITY TO PRODUCE THE COMPLEX NATURAL MENISCAL INTERNAL STRUCTURE. ELECTROHYDRODYNAMIC-BASED PRINTING TECHNOLOGIES HAVE ATTRACTED SIGNIFICANT INTEREST FOR TISSUE ENGINEERING APPLICATIONS DUE TO THEIR HIGH RESOLUTION, EFFICIENCY AND RELATIVELY EASY SETUP. IN THIS STUDY, AN IMPROVED SOLVENT-BASED ELECTROHYDRODYNAMIC JET PRINTING (E-JETTING) TECHNIQUE WAS DEVELOPED TO CREATE ORIENTED, HIGH-RESOLUTION POLYCAPROLACTONE (PCL) FIBERS. THIS IS THE FIRST TIME THAT E-JETTING TECHNIQUE WAS EMPLOYED TO BUILD THREE-DIMENSIONAL (3D) WEDGE-SHAPED MENISCAL SCAFFOLDS, WITH A TAILORED INTERNAL 3D MICROSTRUCTURE, REPLICATING THE NATURAL MENISCUS.
URI: http://scholarbank.nus.edu.sg/handle/10635/107407
Appears in Collections:Ph.D Theses (Open)

Show full item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
LiJL.pdf7.57 MBAdobe PDF

OPEN

NoneView/Download

Page view(s)

218
checked on Oct 19, 2018

Download(s)

64
checked on Oct 19, 2018

Google ScholarTM

Check


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.