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https://scholarbank.nus.edu.sg/handle/10635/107228
Title: | Synthesis of nir-sensitive Au-Au2S nanocolloids for drug delivery | Authors: | Ren, L. Chow, G.M. |
Keywords: | Au-Au2S Cis-platin Drug delivery Nanoparticles Near-infrared |
Issue Date: | 15-Jan-2003 | Citation: | Ren, L.,Chow, G.M. (2003-01-15). Synthesis of nir-sensitive Au-Au2S nanocolloids for drug delivery. Materials Science and Engineering C 23 (1-2) : 113-116. ScholarBank@NUS Repository. | Abstract: | Near IR (NIR) sensitive Au-Au2S nanocolloids were prepared by mixing HAuCl4 and Na2S in aqueous solutions. An anti-tumor drug, cis-platin, was adsorbed onto Au-Au2S nanoparticle surface via the 11-mercaptoundecanoic acid (MUA) layers. The results show that the degree of adsorption of cis-platin onto Au-Au2S nanoparticles was controlled by the solution pH value, and the drug release was sensitive to near-infrared irradiation. The cis-platin-loaded Au-Au2S nanocolloids can be potentially applied as NIR activated drug delivery carrier. © 2002 Elsevier Science B.V. All rights reserved. | Source Title: | Materials Science and Engineering C | URI: | http://scholarbank.nus.edu.sg/handle/10635/107228 | ISSN: | 09284931 |
Appears in Collections: | Staff Publications |
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