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|Title:||Synthesis of nir-sensitive Au-Au2S nanocolloids for drug delivery|
|Citation:||Ren, L.,Chow, G.M. (2003-01-15). Synthesis of nir-sensitive Au-Au2S nanocolloids for drug delivery. Materials Science and Engineering C 23 (1-2) : 113-116. ScholarBank@NUS Repository.|
|Abstract:||Near IR (NIR) sensitive Au-Au2S nanocolloids were prepared by mixing HAuCl4 and Na2S in aqueous solutions. An anti-tumor drug, cis-platin, was adsorbed onto Au-Au2S nanoparticle surface via the 11-mercaptoundecanoic acid (MUA) layers. The results show that the degree of adsorption of cis-platin onto Au-Au2S nanoparticles was controlled by the solution pH value, and the drug release was sensitive to near-infrared irradiation. The cis-platin-loaded Au-Au2S nanocolloids can be potentially applied as NIR activated drug delivery carrier. © 2002 Elsevier Science B.V. All rights reserved.|
|Source Title:||Materials Science and Engineering C|
|Appears in Collections:||Staff Publications|
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