Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/107228
Title: Synthesis of nir-sensitive Au-Au2S nanocolloids for drug delivery
Authors: Ren, L.
Chow, G.M. 
Keywords: Au-Au2S
Cis-platin
Drug delivery
Nanoparticles
Near-infrared
Issue Date: 15-Jan-2003
Source: Ren, L.,Chow, G.M. (2003-01-15). Synthesis of nir-sensitive Au-Au2S nanocolloids for drug delivery. Materials Science and Engineering C 23 (1-2) : 113-116. ScholarBank@NUS Repository.
Abstract: Near IR (NIR) sensitive Au-Au2S nanocolloids were prepared by mixing HAuCl4 and Na2S in aqueous solutions. An anti-tumor drug, cis-platin, was adsorbed onto Au-Au2S nanoparticle surface via the 11-mercaptoundecanoic acid (MUA) layers. The results show that the degree of adsorption of cis-platin onto Au-Au2S nanoparticles was controlled by the solution pH value, and the drug release was sensitive to near-infrared irradiation. The cis-platin-loaded Au-Au2S nanocolloids can be potentially applied as NIR activated drug delivery carrier. © 2002 Elsevier Science B.V. All rights reserved.
Source Title: Materials Science and Engineering C
URI: http://scholarbank.nus.edu.sg/handle/10635/107228
ISSN: 09284931
Appears in Collections:Staff Publications

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