Effects of glucose transport on the incorporation of 32P-inorganic phosphate into phospholipids in Hymenolepis diminuta (cestoda)

Abstract

1. 1. The absorption of glucose and α-methyl-d-glucoside by Hymenolepis diminuta was concentration dependent. 2. 2. α-Methyl-d-glucoside competitively inhibited glucose absorption and was not metabolised by the parasite. 3. 3. α-Methyl-d-glucoside significantly lowered (P < 0.05) the incorporation of 32Pi into all phospholipid classes. 4. 4. Glucose inhibited (P < 0.01) 32Pi incorporation into phosphatidylcholine only. 5. 5. Phlorizin did not affect 32Pi labelling of phospholipids. 6. 6. Serotonin and histamine stimulated (P < 0.01) 32Pi labelling of all phospholipid classes. 7. 7. Radioactivities in water soluble fractions were increased (P < 0.01) in the presence of glucose, serotonin and histamine. © 1987.