Please use this identifier to cite or link to this item: https://doi.org/10.1081/DDC-120028706
Title: Wet Spheronization by Rotary Processing - A Multistage Single-Pot Process for Producing Spheroids
Authors: Gu, L.
Liew, C.V. 
Heng, P.W.S. 
Keywords: Rotary processing
Spheroids
Wet spheronization
Issue Date: 2004
Source: Gu, L., Liew, C.V., Heng, P.W.S. (2004). Wet Spheronization by Rotary Processing - A Multistage Single-Pot Process for Producing Spheroids. Drug Development and Industrial Pharmacy 30 (2) : 111-123. ScholarBank@NUS Repository. https://doi.org/10.1081/DDC-120028706
Abstract: Spheronization is an agglomerative size enlargement process for producing spherical agglomerates that have many technological and therapeutical advantages. Rotary processing is an efficient multistage, single-pot spheroid production method. The rotary processor can be used for spheroid production, drying as well as coating. In the course of spheroid production, centrifugal, fluidizing, and gravitational forces act upon the product from different directions and collectively contribute to the spheroid formation process during rotary processing. The outcome of the process depends on the complex interactions between the equipment, formulation, and process variables.
Source Title: Drug Development and Industrial Pharmacy
URI: http://scholarbank.nus.edu.sg/handle/10635/106510
ISSN: 03639045
DOI: 10.1081/DDC-120028706
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