Please use this identifier to cite or link to this item: https://doi.org/10.1039/c2ob06840k
Title: Scope of direct arylation of fluorinated aromatics with aryl sulfonates
Authors: Chang, J.W.W.
Chia, E.Y.
Chai, C.L.L. 
Seayad, J.
Issue Date: 21-Mar-2012
Citation: Chang, J.W.W., Chia, E.Y., Chai, C.L.L., Seayad, J. (2012-03-21). Scope of direct arylation of fluorinated aromatics with aryl sulfonates. Organic and Biomolecular Chemistry 10 (11) : 2289-2299. ScholarBank@NUS Repository. https://doi.org/10.1039/c2ob06840k
Abstract: The scope and limitations of direct arylation of fluorinated aromatics with aryl sulfonates was examined. Pd(OAc) 2, in the presence of MePhos and KOAc in THF, efficiently catalyzed the direct arylation of fluoro aromatics with aryl triflates under ambient conditions. Sterically hindered triflates and heteroaryl triflates gave good to excellent yields of the cross coupled products using a modified catalyst system which involves Pd(OAc) 2-RuPhos at 100°C. The direct arylation of electron deficient arenes with aryl mesylates is also established using Pd(OAc) 2-SPhos as the catalyst in toluene- tBuOH at 120°C. © The Royal Society of Chemistry 2012.
Source Title: Organic and Biomolecular Chemistry
URI: http://scholarbank.nus.edu.sg/handle/10635/106322
ISSN: 14770520
DOI: 10.1039/c2ob06840k
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

30
checked on Aug 18, 2018

WEB OF SCIENCETM
Citations

30
checked on Jul 17, 2018

Page view(s)

38
checked on Aug 17, 2018

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.