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Title: Relationship between temperature and swelling of methylcellulose in tablets
Authors: Wan, L.S.C. 
Prasad, K.P.P.
Issue Date: 1990
Source: Wan, L.S.C.,Prasad, K.P.P. (1990). Relationship between temperature and swelling of methylcellulose in tablets. Drug Development and Industrial Pharmacy 16 (6) : 945-950. ScholarBank@NUS Repository.
Abstract: The rate of swelling of methylcellulose (MC) films and the maximum swelling attained, decreased with an increase in temperature. The order for the uptake of water at different temperatures by tablets containing varying viscosity grade MC is 37°C > 34°C > 30°C. The higher degree of swelling of MC at low temperatures causes it to block the pores within the tablet and retard water uptake. The disintegration time of the tablets is low at higher temperatures due to enhanced aqueous uptake.
Source Title: Drug Development and Industrial Pharmacy
ISSN: 03639045
Appears in Collections:Staff Publications

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