Quantification of trans -3,4,5,4′-tetramethoxystilbene in rat plasma by HPLC: Application to pharmacokinetic study

Please use this identifier to cite or link to this item: https://doi.org/10.1021/jf1043019

Title:	Quantification of trans -3,4,5,4′-tetramethoxystilbene in rat plasma by HPLC: Application to pharmacokinetic study
Authors:	Lin, H.-S. Zhang, W. Go, M.L. Tringali, C. Spatafora, C. Ho, P.C.
Keywords:	absolute oral bioavailability HPLC pharmacokinetics trans-3,4,5,4′-Tetramethoxystilbene
Issue Date:	23-Feb-2011
Citation:	Lin, H.-S., Zhang, W., Go, M.L., Tringali, C., Spatafora, C., Ho, P.C. (2011-02-23). Quantification of trans -3,4,5,4′-tetramethoxystilbene in rat plasma by HPLC: Application to pharmacokinetic study. Journal of Agricultural and Food Chemistry 59 (4) : 1072-1077. ScholarBank@NUS Repository. https://doi.org/10.1021/jf1043019
Abstract:	A simple HPLC method was established to quantify trans-3,4,5,4′- tetramethoxystilbene (MR-4 or DMU-212) in rat plasma. Chromatographic separation was obtained with a reversed-phase HPLC column through an 11 min gradient delivery of a mixture of acetonitrile and water at a flow rate of 1.5 mL/min at 50 °C. The limit of quantification was 15 ng/mL. The intra- and interday precisions in terms of relative standard deviation were
Source Title:	Journal of Agricultural and Food Chemistry
URI:	http://scholarbank.nus.edu.sg/handle/10635/106278
ISSN:	00218561
DOI:	10.1021/jf1043019
Appears in Collections:	Staff Publications

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