Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.tet.2007.10.046
Title: Practical synthesis of regioisomeric 5(7)-amino-6,7(4,5)-dihydro[1,2,4]triazolo[1,5-a][1,3,5]triazines
Authors: Dolzhenko, A.V. 
Dolzhenko, A.V.
Chui, W.-K. 
Keywords: 1,2,4-Triazoles
5-Azapurines
Fused 1,3,5-triazines
Hydrazides
Tautomerism
Triazolotriazines
Issue Date: 24-Dec-2007
Citation: Dolzhenko, A.V., Dolzhenko, A.V., Chui, W.-K. (2007-12-24). Practical synthesis of regioisomeric 5(7)-amino-6,7(4,5)-dihydro[1,2,4]triazolo[1,5-a][1,3,5]triazines. Tetrahedron 63 (52) : 12888-12895. ScholarBank@NUS Repository. https://doi.org/10.1016/j.tet.2007.10.046
Abstract: A convenient and efficient synthesis of new 5-azapurine derivatives was developed. The regioisomeric 5-amino-6,7-dihydro- and 7-amino-4,5-dihydro[1,2,4]triazolo[1,5-a][1,3,5]triazines were prepared in 3-4 steps from benzhydrazide via complementary and regiospecific routes as a part of our lead finding program. The molecular structures and tautomeric preferences of the compounds obtained were investigated using NMR spectral data and X-ray crystallography. © 2007 Elsevier Ltd. All rights reserved.
Source Title: Tetrahedron
URI: http://scholarbank.nus.edu.sg/handle/10635/106235
ISSN: 00404020
DOI: 10.1016/j.tet.2007.10.046
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

23
checked on May 23, 2018

WEB OF SCIENCETM
Citations

25
checked on May 23, 2018

Page view(s)

24
checked on May 18, 2018

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.