Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.jpba.2008.01.004
Title: Identification of benzamidenafil, a new class of phosphodiesterase-5 inhibitor, as an adulterant in a dietary supplement
Authors: Zou, P.
Hou, P.
Oh, S.S.-Y.
Ge, X.
Bloodworth, B.C.
Low, M.-Y.
Koh, H.-L. 
Keywords: Adulterant
Benzamidenafil
Dietary supplements
Liquid chromatography-mass spectrometry (LC-MS)
Nuclear magnetic resonance (NMR)
PDE-5 inhibitor
Issue Date: 9-Jun-2008
Citation: Zou, P., Hou, P., Oh, S.S.-Y., Ge, X., Bloodworth, B.C., Low, M.-Y., Koh, H.-L. (2008-06-09). Identification of benzamidenafil, a new class of phosphodiesterase-5 inhibitor, as an adulterant in a dietary supplement. Journal of Pharmaceutical and Biomedical Analysis 47 (2) : 255-259. ScholarBank@NUS Repository. https://doi.org/10.1016/j.jpba.2008.01.004
Abstract: A sample labeled to be a natural herbal supplement for the enhancement of sexual function, was sent to Health Sciences Authority (HSA) of Singapore for testing. An unknown compound was detected and isolated from the product. The structure of the unknown compound was identified using LC-UV, high-resolution MS, ESI-MS/MS, IR, and NMR. The compound was characterized as a phosphodiesterase-5 (PDE-5) inhibitor, benzamidenafil. This is the first report of benzamidenafil, representing a new class of PDE-5 inhibitors, as an adulterant of a dietary supplement. © 2008 Elsevier B.V. All rights reserved.
Source Title: Journal of Pharmaceutical and Biomedical Analysis
URI: http://scholarbank.nus.edu.sg/handle/10635/106012
ISSN: 07317085
DOI: 10.1016/j.jpba.2008.01.004
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

28
checked on Aug 14, 2018

WEB OF SCIENCETM
Citations

27
checked on Jul 4, 2018

Page view(s)

18
checked on Jul 6, 2018

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.