Please use this identifier to cite or link to this item:
|Title:||An aqueous medium synthesis and tautomerism study of 3(5)-amino-1,2,4-triazoles|
|Authors:||Dolzhenko, A.V. |
|Source:||Dolzhenko, A.V., Pastorin, G., Dolzhenko, A.V., Chui, W.K. (2009-05-06). An aqueous medium synthesis and tautomerism study of 3(5)-amino-1,2,4-triazoles. Tetrahedron Letters 50 (18) : 2124-2128. ScholarBank@NUS Repository. https://doi.org/10.1016/j.tetlet.2009.02.172|
|Abstract:||A catalyst-free highly efficient synthesis of 3(5)-amino-5(3)-(het)aryl-1,2,4-triazoles in aqueous medium was performed using conventional heating and microwave irradiation. The tautomerism in the products was investigated using NMR spectroscopy and X-ray crystallography. The effects of the substitution, temperature, solvents, and concentration on the tautomerism were studied. The triazoles were found to exist in 1H-forms, the 4H-form was not observed either in solid state or in solution. In general, 5-amino-1,2,4-triazoles were electronically preferred in the tautomeric equilibrium, but some exceptions from the established relationship were also identified. © 2009 Elsevier Ltd. All rights reserved.|
|Source Title:||Tetrahedron Letters|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Feb 22, 2018
WEB OF SCIENCETM
checked on Jan 22, 2018
checked on Feb 19, 2018
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.