Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.gene.2013.08.014
Title: Association of Interleukin-13 SNP rs20541 (Arg>Gln) to allergic rhinitis in an Asian population of ethnic Chinese in Singapore
Authors: Andiappan, A.K.
Rotzschke, O.
Wang, D.Y.
Chew, F.T. 
Keywords: AR
Genetics
IL-13
Rs20541
Singapore Chinese
Issue Date: 25-Oct-2013
Citation: Andiappan, A.K., Rotzschke, O., Wang, D.Y., Chew, F.T. (2013-10-25). Association of Interleukin-13 SNP rs20541 (Arg>Gln) to allergic rhinitis in an Asian population of ethnic Chinese in Singapore. Gene 529 (2) : 357-358. ScholarBank@NUS Repository. https://doi.org/10.1016/j.gene.2013.08.014
Abstract: In this study, we report our findings as we evaluated the association of IL-13 SNP rs20541 to AR as reported in the meta-analysis (Ying, X-J et al., April, Gene 2013) in an Asian population of 1322 ethnic Chinese recruited in Singapore well defined and characterized for allergic rhinitis. The SNP was significantly associated with AR at an odds ratio of 1.57 for the homozygous genotype comparisons indicating a strong risk for AR. This highlights the importance of this mutation in Asian populations for risk towards allergic phenotypes and also warrants further functional work to characterize the mechanism behind this genetic predisposition. © 2013.
Source Title: Gene
URI: http://scholarbank.nus.edu.sg/handle/10635/102278
ISSN: 03781119
DOI: 10.1016/j.gene.2013.08.014
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