Synthesis and bioassay of the eight analogues of the ch503 male pheromone (3-acetoxy-11,19-octacosadien-1-ol) of the Drosophila Melanogaster fruit fly

Please use this identifier to cite or link to this item: https://doi.org/10.1271/bbb.130383

Title:	Synthesis and bioassay of the eight analogues of the ch503 male pheromone (3-acetoxy-11,19-octacosadien-1-ol) of the Drosophila Melanogaster fruit fly
Authors:	Shikichi, Y. Shankar, S. Yew, J.Y. Mori, K.
Keywords:	19-octacosadiyn-1-ol 3-acetoxy-11 3-acetoxy-11 or 19- octacosen-1-ol 3-acetoxyoctacosan- 1-ol Drosophila melanogaster Pheromone
Issue Date:	2013
Citation:	Shikichi, Y., Shankar, S., Yew, J.Y., Mori, K. (2013). Synthesis and bioassay of the eight analogues of the ch503 male pheromone (3-acetoxy-11,19-octacosadien-1-ol) of the Drosophila Melanogaster fruit fly. Bioscience, Biotechnology and Biochemistry 77 (9) : 1931-1938. ScholarBank@NUS Repository. https://doi.org/10.1271/bbb.130383
Abstract:	Eight analogues of (3R,11Z,19Z)-CH503 (3-acetoxy- 11,19-octacosadien-1-ol), the anti-aphrodisiac pheromone of male Drosophila melanogaster, were synthesized for a bioassay. These were the enantiomers of 3-acetoxy- 11,19-octacosadiyn-1-ol (1), 3-acetoxyoctacosan-1-ol (2), (Z)-3-acetoxy-11- octacosen-1-ol (3), and (Z)-3-acetoxy- 19-octacosen-1-ol (4). None of them were pheromonally active, indicating that the two double bonds at C-11 and C-19 were necessary for bioactivity.
Source Title:	Bioscience, Biotechnology and Biochemistry
URI:	http://scholarbank.nus.edu.sg/handle/10635/101796
ISSN:	09168451
DOI:	10.1271/bbb.130383
Appears in Collections:	Staff Publications

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