Please use this identifier to cite or link to this item: https://doi.org/10.1038/ng1286
Title: Repression of AGAMOUS-LIKE 24 is a crucial step in promoting flower development
Authors: Yu, H. 
Ito, T.
Wellmer, F.
Meyerowitz, E.M.
Issue Date: Feb-2004
Citation: Yu, H., Ito, T., Wellmer, F., Meyerowitz, E.M. (2004-02). Repression of AGAMOUS-LIKE 24 is a crucial step in promoting flower development. Nature Genetics 36 (2) : 157-161. ScholarBank@NUS Repository. https://doi.org/10.1038/ng1286
Abstract: Flower development begins as floral meristems arise in succession on the flank of the inflorescence meristem. Floral meristem identity genes LEAFY (LFY) and APETALA1 (AP1) promote establishment and maintenance of floral identity in newly formed floral primordia1-9. Without their activity, the floral primordia develop with inflorescence characteristics. The underlying molecular-genetic mechanism is unknown. Here we show that these phenotypes are due in large part to the ectopic expression of AGAMOUS-LIKE 24 (AGL24), a central regulator of floral meristem identity. We present evidence that AGL24 is an early target of transcriptional repression by LFY and AP1. Without such repression, continued AGL24 expression in floral meristems is sufficient to cause floral reversion regardless of the activation of floral organ identity genes. This indicates that LFY and AP1 promote floral development not only by positively regulating genes activated in flower development, but also by repressing AGL24, a promoter of inflorescence fate.
Source Title: Nature Genetics
URI: http://scholarbank.nus.edu.sg/handle/10635/101564
ISSN: 10614036
DOI: 10.1038/ng1286
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

165
checked on Dec 12, 2018

WEB OF SCIENCETM
Citations

164
checked on Dec 12, 2018

Page view(s)

26
checked on Nov 23, 2018

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.