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|Title:||Proteomic analysis of cellular protein alterations using a hepatitis B virus-producing cellular model|
|Keywords:||Hepatitis B virus|
Two-dimensional gel electrophoresis
|Citation:||Tong, A., Wu, L., Lin, Q., Quek, C.L., Zhao, X., Li, J., Chen, P., Chen, L., Tang, H., Huang, C., Wei, Y.-Q. (2008-05). Proteomic analysis of cellular protein alterations using a hepatitis B virus-producing cellular model. Proteomics 8 (10) : 2012-2023. ScholarBank@NUS Repository. https://doi.org/10.1002/pmic.200700849|
|Abstract:||Hepatitis B virus (HBV) is one of the major etiological factors responsible for acute and chronic liver disease and for the development of hepatocellular carcinoma (HCC). To determine the effects of HBV replication on host cell-protein expression, we utilized 2-DE and MS/MS analysis to compare and identify differentially expressed proteins between an HBV-producing cell line HepG2.2.15 and its parental cell line HepG2. Of the 66 spots identified as differentially expressed (± over twofold, p|
|Appears in Collections:||Staff Publications|
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