Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/101079
Title: Membrane destabilization by monomeric hIAPP observed by imaging fluorescence correlation spectroscopy
Authors: Bag, N.
Ali, A.
Chauhan, V.S.
Wohland, T. 
Mishra, A.
Issue Date: 14-Oct-2013
Citation: Bag, N., Ali, A., Chauhan, V.S., Wohland, T., Mishra, A. (2013-10-14). Membrane destabilization by monomeric hIAPP observed by imaging fluorescence correlation spectroscopy. Chemical Communications 49 (80) : 9155-9157. ScholarBank@NUS Repository.
Abstract: Monomeric hIAPP significantly destabilizes both model and live cell membranes by increasing membrane fluidity. This interaction with membranes happens via carpet formation followed by lipid extraction in a concentration dependent manner and thus we propose that hIAPP aggregation prior to membrane interaction may not be necessary for its cytotoxicity. © 2013 The Royal Society of Chemistry.
Source Title: Chemical Communications
URI: http://scholarbank.nus.edu.sg/handle/10635/101079
ISSN: 13597345
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

16
checked on Mar 6, 2018

WEB OF SCIENCETM
Citations

16
checked on May 7, 2018

Page view(s)

31
checked on May 18, 2018

Google ScholarTM

Check


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.