Computer aided design of FtsZ targeting oligopeptides

Please use this identifier to cite or link to this item: https://doi.org/10.1039/c2ra21886k

Title:	Computer aided design of FtsZ targeting oligopeptides
Authors:	Pieraccini, S. Rendine, S. Jobichen, C. Domadia, P. Sivaraman, J. Francescato, P. Speranza, G. Sironi, M.
Issue Date:	14-Feb-2013
Citation:	Pieraccini, S., Rendine, S., Jobichen, C., Domadia, P., Sivaraman, J., Francescato, P., Speranza, G., Sironi, M. (2013-02-14). Computer aided design of FtsZ targeting oligopeptides. RSC Advances 3 (6) : 1739-1743. ScholarBank@NUS Repository. https://doi.org/10.1039/c2ra21886k
Abstract:	FtsZ is a protein involved in the bacterial division process and is thus an emerging target for antibacterial drugs. The network of interactions between FtsZ monomers necessary for exploitation of its biological function are studied here with molecular dynamics and free energy calculations. The results obtained led to the design of FtsZ targeting peptides which exhibited activity against the function of FtsZ in vitro. © 2012 The Royal Society of Chemistry.
Source Title:	RSC Advances
URI:	http://scholarbank.nus.edu.sg/handle/10635/100316
ISSN:	20462069
DOI:	10.1039/c2ra21886k
Appears in Collections:	Staff Publications

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