Please use this identifier to cite or link to this item:
|Title:||ADME-AP: A database of ADME associated proteins|
|Source:||Sun, L.Z., Ji, Z.L., Chen, X., Wang, J.F., Chen, Y.Z. (2002-12-01). ADME-AP: A database of ADME associated proteins. Bioinformatics 18 (12) : 1699-1700. ScholarBank@NUS Repository. https://doi.org/10.1093/bioinformatics/18.12.1699|
|Abstract:||Summary: Drug absorption, distribution, metabolism and excretion (ADME) often involve interaction of a drug with specific proteins. Knowledge about these ADME-associated proteins is important in facilitating the study of the molecular mechanism of disposition and individual response as well as therapeutic action of drugs. It is also useful in the development and testing of pharmacokinetics prediction tools. Several databases describing specific classes of ADME-associated proteins have appeared. A new database, ADME-associated proteins (ADME-AP), is introduced to provide comprehensive information about all classes of ADME-associated proteins described in the literature including physiological function of each protein, pharmacokinetic effect, ADME classification, direction and driving force of disposition, location and tissue distribution, substrates, synonyms, gene name and protein availability in other species. Cross-links to other databases are also provided to facilitate the access of information about the sequence, 3D structure, function, polymorphisms, genetic disorders, nomenclature, ligand binding properties and related literatures of each protein. ADME-AP currently contains entries for 321 proteins and 964 substrates.|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Apr 2, 2018
WEB OF SCIENCETM
checked on Mar 5, 2018
checked on Apr 20, 2018
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.