Ti, T.K.Yuen, R.Tan, W.SURGERY2016-12-202016-12-201981Ti, T.K., Yuen, R., Tan, W. (1981). Radioimmunoassay for serum gastrin in Singapore Chinese. Singapore Medical Journal 22 (1) : 12-15. ScholarBank@NUS Repository.00375675https://scholarbank.nus.edu.sg/handle/10635/134114Fasting serum gastrin was determined by radioimmunoassay with the Dianabot kit (Tokyo) in 81 Chinese subjects. The mean fasting serum gastrin level in 43 duodenal ulcer patients (73 pg/ml) was higher than that in 18 control subjects (57 pg/ml) though the difference did not reach statistical significance. These levels fall within the range in Caucasians. The findings support the hypothesis that impaired auto-regulation of gastrin release in patients with duodenal ulcer by low antral pH is a contributing factor in duodenal ulcer diathesis. The mean fasting level in 19 gastric ulcer patients (68 pg/ml) was also higher than in the control subjects, but not significantly so. The infrequency of hypergastrinaemia in these gastric ulcer patients is probably due to associated antral gastritis.ArticleNOT_IN_WOS