Yinghuai, Z.Carpenter, K.Bun, C.C.Bahnmueller, S.Ke, C.P.Srid, V.S.Kee, L.W.Hawthorne, M.F.CHEMISTRY2014-10-162014-10-162003-08-18Yinghuai, Z., Carpenter, K., Bun, C.C., Bahnmueller, S., Ke, C.P., Srid, V.S., Kee, L.W., Hawthorne, M.F. (2003-08-18). (R)-binap-mediated asymmetric hydrogenation with a rhodacarborane catalyst in ionic-liquid media. Angewandte Chemie - International Edition 42 (32) : 3792-3795. ScholarBank@NUS Repository. https://doi.org/10.1002/anie.20035127314337851https://scholarbank.nus.edu.sg/handle/10635/92879Unsymmetrical aryl ketones undergo asymmetric hydrogenation in ionic-liquid media in the presence of (R)-binap and a rhodacarborane catalyst derived from the suicide precursor 1 (see scheme). Ketones that are poor substrates for other methods can be hydrogenated in quantitative yields with very high enantioselectivities (97.3-99.5% ee). The novel ionic liquid (N-n-butylpyridinium)+(closo-CB11H12) - provides a superior medium for these reactions.Asymmetric catalysisCarboranesHydrogenationIonic liquidsP ligandsRhodiumArticle000185038000014