Lin, P.Ganesan, A.INSTITUTE OF MOLECULAR & CELL BIOLOGY2014-11-282014-11-281998-03-03Lin, P., Ganesan, A. (1998-03-03). Solid-phase synthesis of peptidomimetic oligomers with a phosphodiesterase backbone. Bioorganic and Medicinal Chemistry Letters 8 (5) : 511-514. ScholarBank@NUS Repository. https://doi.org/10.1016/S0960-894X(98)00064-X0960894Xhttps://scholarbank.nus.edu.sg/handle/10635/112076An unnatural biopolymer is described in which amino acid side-chains are presented along a negatively charged phosphodiester backbone. For this purpose, a series of phosphoramidite monomers was prepared from chiral 1,2-diols. These were efficiently converted into oligomers using standard coupling conditions on an automated DNA synthesizer.Article000072466300022