Please use this identifier to cite or link to this item: https://doi.org/10.1111/j.1365-313X.2010.04182.x
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dc.titleA plant-specific histone H3 lysine 4 demethylase represses the floral transition in Arabidopsis
dc.contributor.authorYang, W.
dc.contributor.authorJiang, D.
dc.contributor.authorJiang, J.
dc.contributor.authorHe, Y.
dc.date.accessioned2014-10-27T08:20:07Z
dc.date.available2014-10-27T08:20:07Z
dc.date.issued2010-05
dc.identifier.citationYang, W., Jiang, D., Jiang, J., He, Y. (2010-05). A plant-specific histone H3 lysine 4 demethylase represses the floral transition in Arabidopsis. Plant Journal 62 (4) : 663-673. ScholarBank@NUS Repository. https://doi.org/10.1111/j.1365-313X.2010.04182.x
dc.identifier.issn09607412
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/99927
dc.description.abstractHistone demethylation regulates chromatin structure and gene expression, and is catalyzed by various histone demethylases. Trimethylation of histone H3 at lysine 4 (H3K4) is coupled to active gene expression; trimethyl H3K4 is demethylated by Jumonj C (JmjC) domain-containing demethylases in mammals. Here we report that a plant-specific JmjC domain-containing protein known as PKDM7B (At4g20400) demethylates trimethyl H3K4. PKDM7B mediates H3K4 demethylation in a key floral promoter, FLOWERING LOCUS T (FT), and an FT homolog, TWIN SISTER OF FT (TSF), and represses their expression to inhibit the floral transition in Arabidopsis. Our findings suggest that there are at least two distinct sub-families of JmjC domain-containing demethylases that demethylate the active trimethyl H3K4 mark in eukaryotic genes, and reveal a plant-specific JmjC domain enzyme capable of H3K4 demethylation. © 2010 Blackwell Publishing Ltd.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1111/j.1365-313X.2010.04182.x
dc.sourceScopus
dc.subjectFlowering
dc.subjectFT
dc.subjectH3K4 demethylase
dc.subjectHistone demethylation
dc.subjectJmjC-domain protein
dc.subjectTSF
dc.typeArticle
dc.contributor.departmentBIOLOGICAL SCIENCES
dc.description.doi10.1111/j.1365-313X.2010.04182.x
dc.description.sourcetitlePlant Journal
dc.description.volume62
dc.description.issue4
dc.description.page663-673
dc.description.codenPLJUE
dc.identifier.isiut000277609500011
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