Please use this identifier to cite or link to this item:
Title: Two-photon fluorescent Bombyx mori silk by molecular recognition functionalization
Authors: Lin, N.
Toh, G.W.
Feng, Y.
Liu, X.Y. 
Xu, H.
Issue Date: 21-Apr-2014
Citation: Lin, N., Toh, G.W., Feng, Y., Liu, X.Y., Xu, H. (2014-04-21). Two-photon fluorescent Bombyx mori silk by molecular recognition functionalization. Journal of Materials Chemistry B 2 (15) : 2136-2143. ScholarBank@NUS Repository.
Abstract: Two-photon fluorescent (TPF) Bombyx mori silk fibers were acquired for bioimaging by molecular recognition functionalization. In this context, 2,7-bis((E)-4-((E)-4-nitrostyryl)styryl)-9,9-dioctyl-9H-fluorene (NF) was adopted to functionalize silkworm silk fibers. NF exhibits a large two-photon absorption cross section, but has a low TPF quantum yield in the solid form due to the side-by-side (π-π) molecular stacking. In terms of the molecular recognition between the nitro groups of NF and the amide groups of silk fibroin, the silk fibers acquire the two-photon fluorescent emission with a significant enhancement of 350% in TPF quantum yield of NF molecules, compared with the solid state. For comparison, two other molecules, 2,7-bis((E)-4-methylstyryl)-9, 9-dioctyl-9H-fluorene (MF1) and 2,7-bis((E)-4-((E)-4-methylstyryl)styryl)-9,9- dioctyl-9H-fluorene (MF2), were selected for similar experiments. These molecules show little effect due to the lack of molecular recognition. The TPF silk scaffolds were obtained, and high quality imaging of NF in cell culture was finally achieved, which has extremely relevant implications for biomedical applications. © 2014 the Partner Organisations.
Source Title: Journal of Materials Chemistry B
ISSN: 20507518
DOI: 10.1039/c3tb21602k
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

Google ScholarTM



Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.