Please use this identifier to cite or link to this item: https://doi.org/10.1529/biophysj.104.052027
DC FieldValue
dc.titleThe stretched intermediate model of B-Z DNA transition
dc.contributor.authorLim, W.
dc.contributor.authorFeng, Y.P.
dc.date.accessioned2014-10-16T09:45:42Z
dc.date.available2014-10-16T09:45:42Z
dc.date.issued2005-03
dc.identifier.citationLim, W., Feng, Y.P. (2005-03). The stretched intermediate model of B-Z DNA transition. Biophysical Journal 88 (3) : 1593-1607. ScholarBank@NUS Repository. https://doi.org/10.1529/biophysj.104.052027
dc.identifier.issn00063495
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/98318
dc.description.abstractThere have been numerous attempts to describe the mechanism of B-Z transition. Our simulations based on the stochastic difference equation with length algorithm show that a short DNA oligomer will tend to unwind and overstretch during the transition. The overstretching of DNA is then understood from the Zhou, Zhang, and Ou-Yang model. Unlike the Harvey model, the stretched intermediate model does not pose any steric dilemma; we are able to show that the chain sense reversal progresses spontaneously using the stretched intermediate model. A nonlinear DNA model is used to describe the origins and mechanism of base rotation in the stretched intermediate state of DNA. We also propose an experiment that can verify the existence of a stretched intermediate state during B-Z transition, thus opening up fresh grounds for experimentation in this field. © 2005 by the Biophysical Society.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1529/biophysj.104.052027
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentPHYSICS
dc.description.doi10.1529/biophysj.104.052027
dc.description.sourcetitleBiophysical Journal
dc.description.volume88
dc.description.issue3
dc.description.page1593-1607
dc.description.codenBIOJA
dc.identifier.isiut000227494600011
Appears in Collections:Staff Publications

Show simple item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

18
checked on May 25, 2020

WEB OF SCIENCETM
Citations

16
checked on May 25, 2020

Page view(s)

51
checked on May 10, 2020

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.