Please use this identifier to cite or link to this item: https://doi.org/10.1039/b923331h
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dc.titleThe use of click chemistry in the emerging field of catalomics
dc.contributor.authorKalesh, K.A.
dc.contributor.authorShi, H.
dc.contributor.authorGe, J.
dc.contributor.authorYao, S.Q.
dc.date.accessioned2014-10-16T08:45:53Z
dc.date.available2014-10-16T08:45:53Z
dc.date.issued2010
dc.identifier.citationKalesh, K.A., Shi, H., Ge, J., Yao, S.Q. (2010). The use of click chemistry in the emerging field of catalomics. Organic and Biomolecular Chemistry 8 (8) : 1749-1762. ScholarBank@NUS Repository. https://doi.org/10.1039/b923331h
dc.identifier.issn14770520
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/95273
dc.description.abstractOf the thousands of known chemical reactions, a handful of reactions, called "click" reactions, stand out with features such as good chemoselectivity, good solvent compatibilities, modularity, minimum synthetic demands, bioorthogonality and high yields. Among them, the Cu(i)-catalyzed 1,3-dipolar cycloaddition reaction between azides and terminal alkynes has emerged as a powerful tool in chemical biology and proteomics. This perspective surveys the significant contributions of click chemistry in catalomics (a sub-area in chemical proteomics), with special emphasis on activity-based protein profiling (ABPP), posttranslational modifications (PTMs) and enzyme inhibitor developments. © 2010 The Royal Society of Chemistry.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1039/b923331h
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentCHEMISTRY
dc.description.doi10.1039/b923331h
dc.description.sourcetitleOrganic and Biomolecular Chemistry
dc.description.volume8
dc.description.issue8
dc.description.page1749-1762
dc.identifier.isiut000276192100001
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