In situ proteome profiling of C75, a covalent bioactive compound with potential anticancer activities

Please use this identifier to cite or link to this item: https://doi.org/10.1021/ol500206w

Title:	In situ proteome profiling of C75, a covalent bioactive compound with potential anticancer activities
Authors:	Cheng, X. Li, L. Uttamchandani, M. Yao, S.Q.
Issue Date:	7-Mar-2014
Citation:	Cheng, X., Li, L., Uttamchandani, M., Yao, S.Q. (2014-03-07). In situ proteome profiling of C75, a covalent bioactive compound with potential anticancer activities. Organic Letters 16 (5) : 1414-1417. ScholarBank@NUS Repository. https://doi.org/10.1021/ol500206w
Abstract:	A library of cell-permeable, minimally tagged C75 analogues was synthesized and used to uncover biological targets in human liver cancer cells. Known targets of C75, namely FASN and CPT1A, together with other unknown targets, including PDIA3, TFRC, and GAPDH, were thus identified. © 2014 American Chemical Society.
Source Title:	Organic Letters
URI:	http://scholarbank.nus.edu.sg/handle/10635/94023
ISSN:	15237060
DOI:	10.1021/ol500206w
Appears in Collections:	Staff Publications

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