1. ScholarBank@NUS
  2. 1. Staff
  3. Staff Publications
Please use this identifier to cite or link to this item: https://doi.org/10.1002/anie.201102094
DC FieldValue
dc.titleHighly enantioselective [3+2] annulation of Morita-Baylis-Hillman adducts mediated by L-threonine-derived phosphines: Synthesis of 3-spirocyclopentene-2- oxindoles having two contiguous quaternary centers
dc.contributor.authorZhong, F.
dc.contributor.authorHan, X.
dc.contributor.authorWang, Y.
dc.contributor.authorLu, Y.
dc.date.accessioned2014-10-16T08:30:16Z
dc.date.available2014-10-16T08:30:16Z
dc.date.issued2011-08-16
dc.identifier.citationZhong, F., Han, X., Wang, Y., Lu, Y. (2011-08-16). Highly enantioselective [3+2] annulation of Morita-Baylis-Hillman adducts mediated by L-threonine-derived phosphines: Synthesis of 3-spirocyclopentene-2- oxindoles having two contiguous quaternary centers. Angewandte Chemie - International Edition 50 (34) : 7837-7841. ScholarBank@NUS Repository. https://doi.org/10.1002/anie.201102094
dc.identifier.issn14337851
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/93943
dc.description.abstractSpiral bound: The Morita-Baylis-Hillman adducts were employed as C 3 synthons in the asymmetric [3+2] annulation with malonitrile substrates using L-threonine-derived 1 as the catalyst (see scheme). The reaction is highly regioselective and stereoselective, and affords optically enriched 3-spirocyclopentene-2-oxindoles containing two contiguous quaternary centers. Boc=tert-butoxycarbonyl, PMB=para-methoxybenzyl, TIPS= triisopropylsilyl. © 2011 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1002/anie.201102094
dc.sourceScopus
dc.subjectamino acids
dc.subjectasymmetric synthesis
dc.subjectcycloaddition
dc.subjectphosphines
dc.subjectspiro compounds
dc.typeArticle
dc.contributor.departmentCHEMISTRY
dc.description.doi10.1002/anie.201102094
dc.description.sourcetitleAngewandte Chemie - International Edition
dc.description.volume50
dc.description.issue34
dc.description.page7837-7841
dc.description.codenACIEA
dc.identifier.isiut000294175700019
Appears in Collections:Staff Publications

Show simple item record
Files in This Item:
There are no files associated with this item.

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.