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|Title:||Fluorescence-activated cell sorting and directed evolution of α-N-acetylgalactosaminidases using a quenched activity-based probe (qABP)||Authors:||Kalidasan, K.
|Issue Date:||21-Aug-2013||Citation:||Kalidasan, K., Su, Y., Wu, X., Yao, S.Q., Uttamchandani, M. (2013-08-21). Fluorescence-activated cell sorting and directed evolution of α-N-acetylgalactosaminidases using a quenched activity-based probe (qABP). Chemical Communications 49 (65) : 7237-7239. ScholarBank@NUS Repository.||Abstract:||An α-N-acetylgalactosamine-containing quenched activity-based probe (qABP) was designed and successfully synthesized, and it was subsequently used in directed enzyme evolution experiments aided by fluorescence-activated cell sorting (FACS) for the discovery of an α-N-acetylgalactosaminidase variant with improved catalytic activity. © 2013 The Royal Society of Chemistry.||Source Title:||Chemical Communications||URI:||http://scholarbank.nus.edu.sg/handle/10635/93822||ISSN:||13597345|
|Appears in Collections:||Staff Publications|
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