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|Title:||Enantioselective organocatalytic synthesis of medicinally privileged 2-amino-4H-chromene-3-carbonitriles via a cascade process||Authors:||Du, Z.
|Issue Date:||16-Nov-2011||Citation:||Du, Z., Siau, W.-Y., Wang, J. (2011-11-16). Enantioselective organocatalytic synthesis of medicinally privileged 2-amino-4H-chromene-3-carbonitriles via a cascade process. Tetrahedron Letters 52 (46) : 6137-6141. ScholarBank@NUS Repository. https://doi.org/10.1016/j.tetlet.2011.09.030||Abstract:||An efficient organocatalytic cascade approach toward medicinally privileged 2-amino-4H-chromene-3-carbonitriles is reported. The enantioselective synthesis of these compounds is achieved in high yields and good to high ee values (up to 96% yield and 89% ee) using bifunctional amine-thiourea organocatalysts developed in our laboratory. © 2011 Elsevier Ltd. All rights reserved.||Source Title:||Tetrahedron Letters||URI:||http://scholarbank.nus.edu.sg/handle/10635/93740||ISSN:||00404039||DOI:||10.1016/j.tetlet.2011.09.030|
|Appears in Collections:||Staff Publications|
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