Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/93127
DC FieldValue
dc.titleApplication of micro-solid-phase extraction for the determination of persistent organic pollutants in tissue samples
dc.contributor.authorBasheer, C.
dc.contributor.authorNarasimhan, K.
dc.contributor.authorYin, M.
dc.contributor.authorZhao, C.
dc.contributor.authorChoolani, M.
dc.contributor.authorLee, H.K.
dc.date.accessioned2014-10-16T08:20:42Z
dc.date.available2014-10-16T08:20:42Z
dc.date.issued2008-04-04
dc.identifier.citationBasheer, C., Narasimhan, K., Yin, M., Zhao, C., Choolani, M., Lee, H.K. (2008-04-04). Application of micro-solid-phase extraction for the determination of persistent organic pollutants in tissue samples. Journal of Chromatography A 1186 (1-2) : 358-364. ScholarBank@NUS Repository.
dc.identifier.issn00219673
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/93127
dc.description.abstractA novel, simple and efficient method for determining persistent organic pollutants (POPs) in tissue samples has been developed. This technique involves the use of simultaneous microwave-assisted digestion (MAD) and micro-solid-phase extraction (μ-SPE), in which the sorbent is held within a propylene membrane envelope, with gas chromatographic-mass spectrometric (GC-MS) analysis. The POPs studied included eleven organochlorine pesticides and five polychlorinated biphenyl congeners. Optimization of the MAD-μ-SPE parameters was performed. The relative standard deviations (RSDs) of the method ranged from 0.14 to 12.7%. Correlation coefficients up to 0.9999 were obtained across a concentration range of 1.25-50 ng g-1. The method detection limits for POPs ranged from 0.002 to 0.009 ng g-1. A preliminary study applying the MAD-μ-SPE procedure to human ovarian cancer tissue showed that it was capable of detecting the presence of a wide spectrum of different POPs in benign and malignant tumors. © 2007 Elsevier B.V. All rights reserved.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/j.chroma.2007.10.015
dc.sourceScopus
dc.subjectMicro-solid phase extraction
dc.subjectMicrowave-assisted extraction
dc.subjectOvarian cancer
dc.subjectPersistent organic pollutants
dc.typeArticle
dc.contributor.departmentCHEMISTRY
dc.description.sourcetitleJournal of Chromatography A
dc.description.volume1186
dc.description.issue1-2
dc.description.page358-364
dc.description.codenJCRAE
dc.identifier.isiut000254884700030
Appears in Collections:Staff Publications

Show simple item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

55
checked on Mar 8, 2018

WEB OF SCIENCETM
Citations

66
checked on Sep 21, 2021

Page view(s)

90
checked on Jan 27, 2022

Google ScholarTM

Check


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.