Please use this identifier to cite or link to this item: https://doi.org/10.1016/0040-4020(96)00552-2
Title: A novel improved procedure for the synthesis of oxazoles
Authors: Huang, W. 
Pei, J. 
Chen, B.
Pei, W.
Ye, X.
Issue Date: 22-Jul-1996
Citation: Huang, W., Pei, J., Chen, B., Pei, W., Ye, X. (1996-07-22). A novel improved procedure for the synthesis of oxazoles. Tetrahedron 52 (30) : 10131-10136. ScholarBank@NUS Repository. https://doi.org/10.1016/0040-4020(96)00552-2
Abstract: In the present work a novel improved and convenient procedure for the synthesis of oxazoles has been developed. Acetamide, instead of ammonium acetate, was used to react with phenacyl benzoates in boiling xylene in the presence of BF3/Et2O as the catalyst. According to this new synthetic route, nine oxazole compounds were readily prepared as single products in reasonably high yields. On the basis of the experimental results, a plausible mechanism of this reaction is proposed.
Source Title: Tetrahedron
URI: http://scholarbank.nus.edu.sg/handle/10635/92977
ISSN: 00404020
DOI: 10.1016/0040-4020(96)00552-2
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