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Title: Flow dynamics of immobilized enzyme reactors
Authors: Ching, C.B. 
Ho, Y.Y.
Issue Date: Nov-1984
Citation: Ching, C.B., Ho, Y.Y. (1984-11). Flow dynamics of immobilized enzyme reactors. Applied Microbiology and Biotechnology 20 (5) : 303-309. ScholarBank@NUS Repository.
Abstract: Enzymic conversion of glucose to fructose was carried out in a packed bed and in a fluidized bed reactor. The flow dynamics of these two flow systems, loaded with two different types of immobilized loaded with two different types of immobilized glucose isomerase particles, were studied. The theoretical RTD curve calculated from the axial dispersed plug flow model equation was matched to the experimental RTD curve by an optimization technique. The effect of fluid velocity on the extent of liquid dispersion was established. Theoretical predictions on the conversion of glucose to fructose were calculated using three mathematical models, namely, a plug flow model, a continuous stirred tank reactor (CSTR) model and an axial dispersed plug flow model. The experimental results showed that the axial dispersed plug flow model was superior in predicting the performance of both the packed bed and fluidized bed reactor. © 1984 Springer-Verlag.
Source Title: Applied Microbiology and Biotechnology
ISSN: 01757598
DOI: 10.1007/BF00270590
Appears in Collections:Staff Publications

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