Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/90755
DC FieldValue
dc.titleTreatment planning of cancer dendritic cell therapy using multi-objective optimization
dc.contributor.authorLakshmi Kiran, K.
dc.contributor.authorLakshminarayanan, S.
dc.date.accessioned2014-10-09T07:08:45Z
dc.date.available2014-10-09T07:08:45Z
dc.date.issued2009
dc.identifier.citationLakshmi Kiran, K.,Lakshminarayanan, S. (2009). Treatment planning of cancer dendritic cell therapy using multi-objective optimization. IFAC Proceedings Volumes (IFAC-PapersOnline) 7 (PART 1) : 109-116. ScholarBank@NUS Repository.
dc.identifier.isbn9783902661548
dc.identifier.issn14746670
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/90755
dc.description.abstractCancer immunotherapy is one of the emerging therapies for cancer treatment where immune cells are guided to fight against cancer. Clinical immunologists are proposing different ideas to stimulate the immune cells and dendritic cell therapy is one among them. Like, other treatment modalities, the challenge in dendritic cell therapy is when and how much dendritic cells should be administered. In this work we use a mathematical model which elucidates the activation of the helper T-cells and cytotoxic T-cells by the intervention of dendritic cells. The objective is to minimize the tumor cells for a given input of dendritic cells. Then multi-objective optimization is applied on the model to design the treatment planning in order to achieve the objective.
dc.sourceScopus
dc.subjectCancer
dc.subjectDendritic cell therapy
dc.subjectImmune system
dc.subjectMathematical model
dc.subjectMulti-objective optimization
dc.typeConference Paper
dc.contributor.departmentCHEMICAL & BIOMOLECULAR ENGINEERING
dc.description.sourcetitleIFAC Proceedings Volumes (IFAC-PapersOnline)
dc.description.volume7
dc.description.issuePART 1
dc.description.page109-116
dc.identifier.isiutNOT_IN_WOS
Appears in Collections:Staff Publications

Show simple item record
Files in This Item:
There are no files associated with this item.

Page view(s)

32
checked on Dec 28, 2019

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.