Please use this identifier to cite or link to this item:
https://doi.org/10.1016/j.biomaterials.2007.08.039
Title: | Solvent-free atom transfer radical polymerization for the preparation of poly(poly(ethyleneglycol) monomethacrylate)-grafted Fe3O4 nanoparticles: Synthesis, characterization and cellular uptake | Authors: | Fan, Q.-L. Neoh, K.-G. Kang, E.-T. Shuter, B. Wang, S.-C. |
Keywords: | ATRP Magnetic nanoparticle MRI PEGMA Solvent-free |
Issue Date: | Dec-2007 | Citation: | Fan, Q.-L., Neoh, K.-G., Kang, E.-T., Shuter, B., Wang, S.-C. (2007-12). Solvent-free atom transfer radical polymerization for the preparation of poly(poly(ethyleneglycol) monomethacrylate)-grafted Fe3O4 nanoparticles: Synthesis, characterization and cellular uptake. Biomaterials 28 (36) : 5426-5436. ScholarBank@NUS Repository. https://doi.org/10.1016/j.biomaterials.2007.08.039 | Abstract: | Poly(poly(ethyleneglycol) monomethacrylate) (P(PEGMA))-grafted magnetic nanoparticles (MNPs) were successfully prepared via a solvent-free atom transfer radical polymerization (ATRP) method. The macroinitiators were immobilized on the surface of 6.4±0.8 nm Fe3O4 nanoparticles via effective ligand exchange of oleic acid with 3-chloropropionic acid (CPA), which rendered the nanoparticles soluble in the PEGMA monomer. The so-obtained P(PEGMA)-grafted MNPs have a uniform hydrodynamic particle size of 36.0±1.2 nm. The successful grafting of P(PEGMA) on the MNP surface was ascertained from FTIR and XPS analyses. The uptake of the MNPs by macrophage cells is reduced by two-orders of magnitude to | Source Title: | Biomaterials | URI: | http://scholarbank.nus.edu.sg/handle/10635/90188 | ISSN: | 01429612 | DOI: | 10.1016/j.biomaterials.2007.08.039 |
Appears in Collections: | Staff Publications |
Show full item record
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.