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Title: Design and performance study of a novel immobilized hollow fiber membrane bioreactor
Authors: Yang, P.
Teo, W.-K. 
Ting, Y.-P. 
Keywords: Cell viability
Dual-layer hollow fiber
Membrane bioreactor
Issue Date: Jan-2006
Citation: Yang, P., Teo, W.-K., Ting, Y.-P. (2006-01). Design and performance study of a novel immobilized hollow fiber membrane bioreactor. Bioresource Technology 97 (1) : 39-46. ScholarBank@NUS Repository.
Abstract: A dual-layer coaxial hollow fiber (DLHF) bioreactor for cell immobilization developed to overcome nutrients transport limitation is presented. Cells were contained in the annular space between two coaxial hollow fibers, and nutrients were supplied by a forced convective transport from the shell side through the annular space to the lumen side. With judicious selection of the membrane materials, a low operating transmembrane pressure of 50 kPa, and using E. coli as the model organism, a high cell density of 1011 cells/mL annular space volume and a high cell viability of (up to 80%) were obtained. © 2005 Elsevier Ltd. All rights reserved.
Source Title: Bioresource Technology
ISSN: 09608524
DOI: 10.1016/j.biortech.2005.02.029
Appears in Collections:Staff Publications

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