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Title: Amplification of interference color by using liquid crystal for protein detection
Authors: Zhu, Q.
Yang, K.-L. 
Issue Date: 9-Dec-2013
Citation: Zhu, Q., Yang, K.-L. (2013-12-09). Amplification of interference color by using liquid crystal for protein detection. Applied Physics Letters 103 (24) : -. ScholarBank@NUS Repository.
Abstract: Micrometer-sized, periodic protein lines printed on a solid surface cause interference color which is invisible to the naked eye. However, the interference color can be amplified by using a thin layer of liquid crystal (LC) covered on the surface to form a phase diffraction grating. Strong interference color can thus be observed under ambient light. By using the LC-amplified interference color, we demonstrate naked-eye detection of a model protein - immunoglobulin G (IgG). Limit of detection can reach 20 μg/ml of IgG without using any instrumentation. This detection method is potentially useful for the development of low-cost and portable biosensors. © 2013 AIP Publishing LLC.
Source Title: Applied Physics Letters
ISSN: 00036951
DOI: 10.1063/1.4844835
Appears in Collections:Staff Publications

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