Please use this identifier to cite or link to this item:
|Title:||Poly(ester urethane)s consisting of poly[(R)-3-hydroxybutyrate] and poly(ethylene glycol) as candidate biomaterials: Characterization and mechanical property study||Authors:||Li, X.
|Issue Date:||Sep-2005||Citation:||Li, X., Loh, X.J., Wang, K., He, C., Li, J. (2005-09). Poly(ester urethane)s consisting of poly[(R)-3-hydroxybutyrate] and poly(ethylene glycol) as candidate biomaterials: Characterization and mechanical property study. Biomacromolecules 6 (5) : 2740-2747. ScholarBank@NUS Repository. https://doi.org/10.1021/bm050234g||Abstract:||Poly(ester urethane)s with poly[(R)-3-hydroxybutyrate] (PHB) as the hard and hydrophobic segment and poly(ethylene glycol) (PEG) as the soft and hydrophilic segment were synthesized from telechelic hydroxylated PHB (PHB-diol) and PEG using 1,6-hexamethylene diisocyanate as a nontoxic coupling reagent. Their chemical structures and molecular characteristics were studied by gel permeation chromatography, 1H NMR, and Fourier transform infrared spectroscopy. Results of differential scanning calorimetry and X-ray diffraction indicated that the PHB segment and PEG segment in the poly(ester urethane)s formed separate crystalline phases with lower crystallinity and a lower melting point than those of their corresponding precursors, except no PHB crystalline phase was observed in those with a relatively low PHB fraction. Thermogravimetric analysis showed that the poly(ester urethane)s had better thermal stability than their precursors. The segment compositions were calculated from the two-step thermal decomposition profiles, which were in good agreement with those obtained from 1H NMR. Water contact angle measurement and water swelling analysis revealed that both surface hydrophilicity and bulk hydrophilicity of the poly(ester urethane)s were enhanced by incorporating the PEG segment into PHB polymer chains. The mechanical properties of the poly(ester urethane)s were also assessed by tensile strength measurement. It was found that the poly(ester urethane)s were ductile, while natural source PHB is brittle. Young's modulus and the stress at break increased with increasing PHB segment length or PEG segment length, whereas the strain at break increased with increasing PEG segment length or decreasing PHB segment length. © 2005 American Chemical Society.||Source Title:||Biomacromolecules||URI:||http://scholarbank.nus.edu.sg/handle/10635/88049||ISSN:||15257797||DOI:||10.1021/bm050234g|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Jan 20, 2020
WEB OF SCIENCETM
checked on Jul 10, 2019
checked on Jan 26, 2020
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.