Please use this identifier to cite or link to this item: https://doi.org/10.1364/OE.17.002423
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dc.titleNumerical study of effects of light polarization, scatterer sizes and orientations on near-field coherent anti-Stokes Raman scattering microscopy
dc.contributor.authorLin, J.
dc.contributor.authorWang, H.
dc.contributor.authorZheng, W.
dc.contributor.authorLu, F.
dc.contributor.authorSheppard, C.
dc.contributor.authorHuang, Z.
dc.date.accessioned2014-10-08T09:46:22Z
dc.date.available2014-10-08T09:46:22Z
dc.date.issued2009-02-16
dc.identifier.citationLin, J., Wang, H., Zheng, W., Lu, F., Sheppard, C., Huang, Z. (2009-02-16). Numerical study of effects of light polarization, scatterer sizes and orientations on near-field coherent anti-Stokes Raman scattering microscopy. Optics Express 17 (4) : 2423-2434. ScholarBank@NUS Repository. https://doi.org/10.1364/OE.17.002423
dc.identifier.issn10944087
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/88000
dc.description.abstractWe employ the finite-difference time-domain (FDTD) technique as a numerical approach to studying the effects of polarization, scatterers' sizes and orientations on near-field coherent anti-Stokes Raman scattering (CARS) microscopy imaging. The results show that to acquire better image contrast and larger near-field CARS signals, the scatterers with diameters of less than three-eighths of the pump field wavelength (λp) are preferable to be oriented along the polarization direction of the excitation light fields. It is also found that when the scatterers' sizes are smaller than half a wavelength of the pump field, the perpendicular polarization component of the induced near-field CARS radiations is strictly confined within the regions at the scatterer-water interface or the subsurface of scatterers, yielding a high image contrast (up to 200) with a spatial resolution of λp/16. This study indicates that perpendicular polarization components of near-field CARS microscopy could be used to uncover very fine structures of intra- and/or inter- cellular organelles in cells with nanoscale resolutions. © 2009 Optical Society of America.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1364/OE.17.002423
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentBIOENGINEERING
dc.description.doi10.1364/OE.17.002423
dc.description.sourcetitleOptics Express
dc.description.volume17
dc.description.issue4
dc.description.page2423-2434
dc.identifier.isiut000263432500036
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