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https://doi.org/10.1016/j.jmbbm.2013.03.009
| Title: | Administration of PTH and ibandronate increases ovariectomized rat compact bone viscoelasticity | Authors: | Yang, X. Teoh, S.-H. DasDe, S. Lee, T. |
Keywords: | DMA Osteoporosis treatment Tanδ Viscoelasticity |
Issue Date: | Jun-2013 | Citation: | Yang, X., Teoh, S.-H., DasDe, S., Lee, T. (2013-06). Administration of PTH and ibandronate increases ovariectomized rat compact bone viscoelasticity. Journal of the Mechanical Behavior of Biomedical Materials 22 : 51-58. ScholarBank@NUS Repository. https://doi.org/10.1016/j.jmbbm.2013.03.009 | Abstract: | In this study, the bone mineral density (BMD), geometry, macroscopic viscoelastic properties and mechanical strength in five different groups of Sprague-Dawley rats (sham operated, ovariectomized with vehicle, parathyroid hormone and/or ibandronate administration) were examined by peripheral quantitative computed tomography (pQCT), dynamic mechanical analysis (DMA) and three-point bending test. At the end of the study, storage modulus (E'), loss tangent (tanδ), ultimate force (Fu) and stiffness (S) had greatly decreased in vehicle-treated ovariectomized group as compared to sham group (p | Source Title: | Journal of the Mechanical Behavior of Biomedical Materials | URI: | http://scholarbank.nus.edu.sg/handle/10635/87703 | ISSN: | 17516161 | DOI: | 10.1016/j.jmbbm.2013.03.009 |
| Appears in Collections: | Staff Publications |
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