Please use this identifier to cite or link to this item:
Title: Fabrication of porous electrospun nanofibres
Authors: Zhang, Y.Z. 
Feng, Y. 
Huang, Z.-M.
Ramakrishna, S. 
Lim, C.T. 
Issue Date: 14-Feb-2006
Citation: Zhang, Y.Z., Feng, Y., Huang, Z.-M., Ramakrishna, S., Lim, C.T. (2006-02-14). Fabrication of porous electrospun nanofibres. Nanotechnology 17 (3) : 901-908. ScholarBank@NUS Repository.
Abstract: Immiscible biopolymers of gelatin (Gt) and polycaprolactone (PCL) were first electrospun into a biomimicking composite fibre of Gt/PCL. Based on a phase separation study of the electrospun fibres, a leaching method was employed to generate 3D porous nanofibres by selectively removing the water soluble component of gelatin in a 37 °C aqueous solution of phosphate buffered saline. It was found that leaching treatment gave rise to a unique nanotopography containing grooves, ridges and elliptical pores on the surface as well as inside of the resultant individual nanofibres. Brunauer-Emmett-Teller (BET) area measurement indicated that the formed 3D porous fibres also brought in a pronounced increase of the surface area of fibres. The BET surface area of the porous fibres was observed to be about 2.4 times that of the precursor fibres, up to 15.84 m2 g-1 at its relatively large size of 800 nm diameter. The 3D porous fibres herein prepared could have considerable value for uses in developing highly integrated cell-scaffold tissue complexes and other industrial applications. © 2006 IOP Publishing Ltd.
Source Title: Nanotechnology
ISSN: 09574484
DOI: 10.1088/0957-4484/17/3/047
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.


checked on Feb 19, 2020


checked on Feb 19, 2020

Page view(s)

checked on Feb 16, 2020

Google ScholarTM



Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.