Please use this identifier to cite or link to this item:
https://scholarbank.nus.edu.sg/handle/10635/79599
DC Field | Value | |
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dc.title | BIOINFORMATICS ANALYSIS OF CYCLIN-DEPENDENT KINASE 5: INSIGHTS TO DRUG DISCOVERY | |
dc.contributor.author | KOSARAJU VAMSI KRISHNA | |
dc.date.accessioned | 2014-09-05T18:00:16Z | |
dc.date.available | 2014-09-05T18:00:16Z | |
dc.date.issued | 2013-01-14 | |
dc.identifier.citation | KOSARAJU VAMSI KRISHNA (2013-01-14). BIOINFORMATICS ANALYSIS OF CYCLIN-DEPENDENT KINASE 5: INSIGHTS TO DRUG DISCOVERY. ScholarBank@NUS Repository. | |
dc.identifier.uri | http://scholarbank.nus.edu.sg/handle/10635/79599 | |
dc.description.abstract | This thesis examines how CDK5 can be targeted in different ways as well as advantages and disadvantages various methods. Methodologies developed in this work definitely throw light on new insights to design CDK5 selective drugs. Various methodologies were applied to understand possibilities of targeting cdk5 such as structural modeling, protein-ligand interactions, structure based drug design, and advanced techniques such as peptide based drug design, design of dynamic blockers. . These computational efforts are expected throw light on designing cdk5 selective inhibitors. | |
dc.language.iso | en | |
dc.subject | cyclin dependent kinase drug discovery | |
dc.type | Thesis | |
dc.contributor.department | CHEMISTRY | |
dc.contributor.supervisor | FAN WAI YIP | |
dc.contributor.supervisor | YAO SHAO QIN | |
dc.description.degree | Ph.D | |
dc.description.degreeconferred | DOCTOR OF PHILOSOPHY | |
dc.identifier.isiut | NOT_IN_WOS | |
Appears in Collections: | Ph.D Theses (Open) |
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Complete_thesis_SM.pdf | 10.46 MB | Adobe PDF | OPEN | None | View/Download |
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