Please use this identifier to cite or link to this item:
https://doi.org/10.1039/c0an00144a
Title: | Upconversion nanoparticles in biological labeling, imaging, and therapy | Authors: | Wang, F. Banerjee, D. Liu, Y. Chen, X. Liu, X. |
Issue Date: | Aug-2010 | Citation: | Wang, F., Banerjee, D., Liu, Y., Chen, X., Liu, X. (2010-08). Upconversion nanoparticles in biological labeling, imaging, and therapy. Analyst 135 (8) : 1839-1854. ScholarBank@NUS Repository. https://doi.org/10.1039/c0an00144a | Abstract: | Upconversion refers to non-linear optical processes that convert two or more low-energy pump photons to a higher-energy output photon. After being recognized in the mid-1960s, upconversion has attracted significant research interest for its applications in optical devices such as infrared quantum counter detectors and compact solid-state lasers. Over the past decade, upconversion has become more prominent in biological sciences as the preparation of high-quality lanthanide-doped nanoparticles has become increasingly routine. Owing to their small physical dimensions and biocompatibility, upconversion nanoparticles can be easily coupled to proteins or other biological macromolecular systems and used in a variety of assay formats ranging from bio-detection to cancer therapy. In addition, intense visible emission from these nanoparticles under near-infrared excitation, which is less harmful to biological samples and has greater sample penetration depths than conventional ultraviolet excitation, enhances their prospects as luminescent stains in bio-imaging. In this article, we review recent developments in optical biolabeling and bio-imaging involving upconversion nanoparticles, simultaneously bringing to the forefront the desirable characteristics, strengths and weaknesses of these luminescent nanomaterials. © 2010 The Royal Society of Chemistry. | Source Title: | Analyst | URI: | http://scholarbank.nus.edu.sg/handle/10635/77671 | ISSN: | 00032654 | DOI: | 10.1039/c0an00144a |
Appears in Collections: | Staff Publications |
Show full item record
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.