The first example of enantioselective allyl transfer from a linear homoallylic alcohol to an aldehyde

Abstract

(Formula Presented) The first example of enantioselective linear homoallylic alcohol transfer reaction was revealed. In all cases, the whole rearrangement is thermodynamically favorable and a steric effect is the driving force of this reaction. The preservation of the stereocenter and olefin geometry together with the isolation of γ-adduct homoallylic alcohols in one isomeric form have warranted the proposed mechanism.