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https://doi.org/10.1021/cc900063y
Title: | Synthesis of pyrazolo[5,1-d][1,2,3,5]tetrazine-4(3H)-ones | Authors: | Gao, Y. Lam, Y. |
Issue Date: | 11-Jan-2010 | Citation: | Gao, Y., Lam, Y. (2010-01-11). Synthesis of pyrazolo[5,1-d][1,2,3,5]tetrazine-4(3H)-ones. Journal of Combinatorial Chemistry 12 (1) : 69-74. ScholarBank@NUS Repository. https://doi.org/10.1021/cc900063y | Abstract: | A solid-phase synthesis of 5-aminopyrazole has been developed and applied to the preparation of pyrazolo[5,1-d]-[1,2,3,5]tetrazine-4(3H)-ones. In this strategy, a one-pot reaction from 5-aminopyrazoles to the pyrazolo[5,1-d]-[1,2, 3,5]tetrazine-4(3H)-ones which provided the compounds in good yields was demonstrated. Using this synthetic strategy, we prepared a representative set of 16 pyrazolo[5,1-d][l,2,3,5]tetrazine-4(3H)-ones. © 2010 American Chemical Society. | Source Title: | Journal of Combinatorial Chemistry | URI: | http://scholarbank.nus.edu.sg/handle/10635/77187 | ISSN: | 15204766 | DOI: | 10.1021/cc900063y |
Appears in Collections: | Staff Publications |
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