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Please use this identifier to cite or link to this item: https://doi.org/10.1055/s-0032-1317923
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dc.titleSynthesis of 3,4-disubsituted isoxazoles via enamine [3+2] cycloaddition
dc.contributor.authorJia, Q.-F.
dc.contributor.authorBenjamin, P.S.
dc.contributor.authorHuang, J.
dc.contributor.authorDu, Z.
dc.contributor.authorZheng, X.
dc.contributor.authorZhang, K.
dc.contributor.authorConney, A.H.
dc.contributor.authorWang, J.
dc.date.accessioned2014-06-23T05:51:44Z
dc.date.available2014-06-23T05:51:44Z
dc.date.issued2013
dc.identifier.citationJia, Q.-F., Benjamin, P.S., Huang, J., Du, Z., Zheng, X., Zhang, K., Conney, A.H., Wang, J. (2013). Synthesis of 3,4-disubsituted isoxazoles via enamine [3+2] cycloaddition. Synlett 24 (1) : 79-84. ScholarBank@NUS Repository. https://doi.org/10.1055/s-0032-1317923
dc.identifier.issn09365214
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/77170
dc.description.abstractEnamine-triggered [3+2]-cycloaddition reactions of aldehydes and N-hydroximidoyl chlorides in the presence of triethylamine give rise to 3,4-disubstituted isoxazoles upon oxidation of the cycloadduct 3,4,5-trisubstituted 5-(pyrrolidinyl)-4,5-dihydroisoxazoles. This offers a high yielding, regiospecific and metal-free synthetic route for the synthesis of 3,4-disubstituted isoxazoles. © Georg Thieme Verlag Stuttgart · New York.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1055/s-0032-1317923
dc.sourceScopus
dc.subject1,3-dipoles
dc.subject[3+2] cycloaddition
dc.subjectenamines
dc.subjectisoxazole
dc.typeArticle
dc.contributor.departmentCHEMISTRY
dc.description.doi10.1055/s-0032-1317923
dc.description.sourcetitleSynlett
dc.description.volume24
dc.description.issue1
dc.description.page79-84
dc.description.codenSYNLE
dc.identifier.isiut000314696500018
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